Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis
Liberating Technologies, Inc.
- Location
- Holliston, MA + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
Zenith® Fenestrated+ Clinical Study
Cook Research Incorporated
- Location
- Boston, MA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Gilead Sciences
- Location
- Boston, MA + 53 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Rocket Pharmaceuticals Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 8+ · Men only
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Boston, MA + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Celgene
- Location
- Foxborough, MA + 31 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- Boston, MA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Calico Life Sciences LLC
- Location
- Boston, MA + 33 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Bristol-Myers Squibb
- Location
- Newton, MA + 23 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Spyre Therapeutics, Inc.
- Location
- Boston, MA + 25 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Seaport Therapeutics
- Location
- Boston, MA + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Boston, MA + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
Bristol-Myers Squibb
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 13–17
- RecruitingPhase 2
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
- Location
- Springfield, MA + 60 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Prilenia
- Location
- Boston, MA + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Kymera Therapeutics, Inc.
- Location
- Boston, MA + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Appello Pharmaceuticals, Inc.
- Location
- Boston, MA + 29 other US sites
- Eligibility basics
- Ages 30–80
- RecruitingPhase 2
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Anagram Therapeutics, Inc.
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study Comparing Siplizumab With Rabbit Anti-Thymocyte Globulin to Help the Body Accept a Kidney Transplant
Nefro Avillion Clinical Development, LLC
- Location
- Worcester, MA + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Boston, MA + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 1/Phase 2
A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)
Beam Therapeutics Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Amgen
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
GlaxoSmithKline
- Location
- Fall River, MA + 50 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Fall River, MA + 39 other US sites
- Eligibility basics
- Ages 18+