Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Radiation Free Study
Philips Clinical & Medical Affairs Global
- Location
- Worcester, MA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
The THOR IDE Study
Philips Clinical & Medical Affairs Global
- Location
- Fall River, MA + 28 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Boston, MA + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)
Tiziana Life Sciences LTD
- Location
- Boston, MA
- Eligibility basics
- Ages 30–85
- RecruitingPhase 3
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Neurona Therapeutics
- Location
- Boston, MA + 34 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Boston, MA + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 3
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
Vanda Pharmaceuticals
- Location
- Worcester, MA + 18 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
Flo Digital Contraceptive Study
Flo Health Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 18+ · Women only
- Recruiting
KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure
SterileCare Inc.
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 1 mo–18
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Nkarta, Inc.
- Location
- Worcester, MA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Ardelyx
- Location
- Springfield, MA + 108 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Rapamycin Holdings Inc.
- Location
- Boston, MA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
Sangamo Therapeutics
- Location
- Boston, MA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
Life Biosciences Inc.
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 40–85
- Recruiting
An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis
Erchonia Corporation
- Location
- Acton, MA + 1 other US site
- Eligibility basics
- Ages 22–75
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Kodiak Sciences Inc
- Location
- Boston, MA + 47 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
Kodiak Sciences Inc
- Location
- Boston, MA + 47 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Medtronic Terminate AF Study
Medtronic Cardiac Surgery
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
Takeda
- Location
- Boston, MA + 32 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
W.L.Gore & Associates
- Location
- Boston, MA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
AbbVie
- Location
- Boston, MA + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Springfield, MA + 33 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
Arcturus Therapeutics, Inc.
- Location
- Boston, MA + 10 other US sites
- Eligibility basics
- Ages 18+