Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
Hoffmann-La Roche
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 25–65
- Recruiting
J-Valve Transfemoral Pivotal Study
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC
- Location
- Boston, MA + 33 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
SELUTION4BTK Trial
M.A. Med Alliance S.A.
- Location
- Boston, MA + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
Amgen
- Location
- Boston, MA + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Abivax S.A.
- Location
- New Bedford, MA + 23 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
- Location
- Newton, MA + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Takeda
- Location
- Boston, MA + 11 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)
Varian, a Siemens Healthineers Company
- Location
- Boston, MA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial)
Aspa Therapeutics
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Up to age 2
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa
Sumitomo Pharma America, Inc.
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
LimFlow, Inc.
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 18–95
- RecruitingPhase 1
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Amylyx Pharmaceuticals Inc.
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
Paradromics
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 22–75
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- Boston, MA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
ReAlta Life Sciences, Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Any age listed
- Recruiting
WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
Aktiia SA
- Location
- Boston, MA
- Eligibility basics
- Ages 21–85
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Boston, MA + 36 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome
Biomed Industries, Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 5–20 · Women only
- RecruitingPhase 3
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
Krystal Biotech, Inc.
- Location
- Worcester, MA + 4 other US sites
- Eligibility basics
- Ages 6 mo+
- RecruitingPhase 4
A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)
argenx
- Location
- Worcester, MA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Watertown, MA + 20 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Takeda
- Location
- Newton, MA + 18 other US sites
- Eligibility basics
- Ages 16–70
- RecruitingPhase 3
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
Takeda
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution in Subjects With Alopecia Areata
Aldena Therapeutics
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18–55