Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
AbbVie
- Location
- Waltham, MA + 9 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 3
Lumason® Infusion vs. Bolus Administrations
Bracco Diagnostics, Inc
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Takeda
- Location
- Framingham, MA + 77 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
SPYRAL GEMINI Pilot Study
Medtronic Vascular
- Location
- Boston, MA + 11 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
Boston Scientific Corporation
- Location
- Boston, MA + 46 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Merck Sharp & Dohme LLC
- Location
- Newton, MA + 34 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
- Location
- Boston, MA + 40 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Sanofi
- Location
- Boston, MA + 10 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia
Sanofi
- Location
- Boston, MA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease
Sanofi
- Location
- Boston, MA + 20 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated…
Pulnovo Medical, Inc.
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Transition to KPL-387 Monotherapy Dosing & Administration Study
Kiniksa Pharmaceuticals International, plc
- Location
- Boston, MA + 20 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Delivering tAN to Reduce HMB: The LUNA Study
Spark Biomedical, Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 14–45 · Women only
- RecruitingPhase 3
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
Generate Biomedicines
- Location
- Fall River, MA + 21 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 1/Phase 2
Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease
CRISPR Therapeutics AG
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
AbbVie
- Location
- New Bedford, MA + 60 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
Sling Therapeutics, Inc.
- Location
- East Weymouth, MA + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- Watertown, MA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease
Calico Life Sciences LLC
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 6 mo+
- RecruitingPhase 2
Strategy for Improving Stroke Treatment Response
Translational Sciences, Inc.
- Location
- Boston, MA + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Sanofi
- Location
- Boston, MA + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- Boston, MA + 16 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Apreo Health, Inc.
- Location
- Boston, MA + 17 other US sites
- Eligibility basics
- Ages 40–84
- RecruitingPhase 2/Phase 3
Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387
Kiniksa Pharmaceuticals International, plc
- Location
- Boston, MA + 29 other US sites
- Eligibility basics
- Ages 18–80