Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)
Annexon, Inc.
- Location
- Worcester, MA + 19 other US sites
- Eligibility basics
- Ages 8–85
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- Boston, MA + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Sanofi
- Location
- Boston, MA + 72 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
Medtronic Cardiac Ablation Solutions
- Location
- Boston, MA + 20 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
SymBio Pharmaceuticals
- Location
- Boston, MA + 24 other US sites
- Eligibility basics
- Ages 2 mo+
- RecruitingPhase 3
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
Vor Biopharma
- Location
- Boston, MA + 46 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited
- Location
- Brookline, MA + 10 other US sites
- Eligibility basics
- Ages 3–12
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Methuen, MA + 21 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Sonavex, Inc.
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18–84
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Boston, MA + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
- Location
- Boston, MA + 27 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- Boston, MA + 91 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Bristol-Myers Squibb
- Location
- Newton, MA + 10 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Biotronik, Inc.
- Location
- Boston, MA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Crinetics Pharmaceuticals Inc.
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Sanofi
- Location
- Worcester, MA + 36 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 2
A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Sanofi
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain
Brixton Biosciences, Inc.
- Location
- Burlington, MA + 6 other US sites
- Eligibility basics
- Ages 22–80
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Boston, MA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Boston, MA + 111 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With…
Cabaletta Bio
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Cabaletta Bio
- Location
- Boston, MA + 29 other US sites
- Eligibility basics
- Ages 6–75
- RecruitingPhase 3
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Akero Therapeutics, Inc
- Location
- New Bedford, MA + 131 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)
Pfizer
- Location
- Boston, MA + 10 other US sites
- Eligibility basics
- Up to age 10 mo