Location · Springfield, MO
Clinical trials in Springfield, MO
29 recruiting studies have a site in Springfield, and 10 of them accept healthy volunteers.
29 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
2 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$10,300
Study of an Investigational Drug in Adults with Overweight or Obesity (Study #250061)
QPS Missouri · Springfield, MO
Multiple return visits and daily at-home dosing.
Male/Female
View study & apply (opens in a new tab)Opens QPS Missouri’s page for this exact study
Pays up to
$5,250
Breastfeeding Study: Investigational Birth Control Patch (Study #262088)
QPS Missouri · Springfield, MO
One overnight stay and multiple outpatient return visits. For healthy women currently breastfeeding, at least 6 weeks postpartum.
Female
View study & apply (opens in a new tab)Opens QPS Missouri’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 5 other US sites
- Eligibility basics
- Ages 12–30
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Springfield, MO + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Springfield, MO + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 3
A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults
Pfizer
- Location
- Springfield, MO + 36 other US sites
- Eligibility basics
- Ages 18–49
- RecruitingPhase 3
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Springfield, MO + 111 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Hoffmann-La Roche
- Location
- Springfield, MO + 43 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Tempus AI
- Location
- Springfield, MO + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
- Location
- Springfield, MO + 59 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Springfield, MO + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Springfield, MO + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Springfield, MO + 42 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- Springfield, MO + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Springfield, MO + 46 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
Novo Nordisk A/S
- Location
- Springfield, MO + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Axsome Therapeutics, Inc.
- Location
- Springfield, MO + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
Eli Lilly and Company
- Location
- Springfield, MO + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Eli Lilly and Company
- Location
- Springfield, MO + 35 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Springfield, MO + 111 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Springfield, MO + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Springfield, MO + 62 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
Pfizer
- Location
- Springfield, MO + 30 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
Eli Lilly and Company
- Location
- Springfield, MO + 35 other US sites
- Eligibility basics
- Ages 18+