Heart & blood pressure · Pennsylvania
Heart and blood pressure studies in Pennsylvania
92 studies have at least one recruiting site in Pennsylvania. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
92 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
Starlight Cardiovascular Inc
- Location
- Philadelphia, PA + 7 other US sites
- Eligibility basics
- Up to age 6 mo
- RecruitingPhase 2
Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.
XyloCor Therapeutics, Inc.
- Location
- Allentown, PA + 12 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
BrioHealth Solutions, Inc.
- Location
- Philadelphia, PA + 46 other US sites
- Eligibility basics
- Ages 18–100
- Recruiting
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
Medtronic Cardiac Ablation Solutions
- Location
- Philadelphia, PA + 5 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC
- Location
- Philadelphia, PA + 19 other US sites
- Eligibility basics
- Ages 1 mo–17
- RecruitingPhase 1/Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.
- Location
- Philadelphia, PA + 6 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
- Location
- Abington, PA + 31 other US sites
- Eligibility basics
- Ages 21+
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Harrisburg, PA + 42 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- Philadelphia, PA + 39 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
FORWARD CAD IDE Study
Shockwave Medical, Inc.
- Location
- York, PA + 27 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Zona Health, Inc
- Location
- Pittsburgh, PA + 9 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Philadelphia, PA + 46 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Hershey, PA + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Philadelphia, PA + 29 other US sites
- Eligibility basics
- Ages 50–80
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Abington, PA + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- Philadelphia, PA + 19 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Medtronic Terminate AF Study
Medtronic Cardiac Surgery
- Location
- Pittsburgh, PA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Merck Sharp & Dohme LLC
- Location
- Philadelphia, PA + 8 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 3
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
Amgen
- Location
- Philadelphia, PA + 5 other US sites
- Eligibility basics
- Ages 35–80
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- Lancaster, PA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels
NewAmsterdam Pharma
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Philadelphia, PA + 36 other US sites
- Eligibility basics
- Ages 18–90
- Recruiting
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study
Vektor Medical
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 22+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.