Heart & blood pressure · Pennsylvania
Heart and blood pressure studies in Pennsylvania
92 studies have at least one recruiting site in Pennsylvania. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
92 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics
- Location
- Camp Hill, PA + 80 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Reprieve Cardiovascular, Inc
- Location
- Philadelphia, PA + 33 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Insmed Incorporated
- Location
- Philadelphia, PA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Insmed Incorporated
- Location
- Philadelphia, PA + 10 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Tempus AI
- Location
- Philadelphia, PA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
AllRock Bio, Inc.
- Location
- Philadelphia, PA + 10 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
Eli Lilly and Company
- Location
- York, PA + 12 other US sites
- Eligibility basics
- Ages 45–80
- RecruitingPhase 2
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Eli Lilly and Company
- Location
- West Chester, PA + 28 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Media, PA + 68 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Zenith® Fenestrated+ Clinical Study
Cook Research Incorporated
- Location
- Philadelphia, PA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Rocket Pharmaceuticals Inc.
- Location
- Philadelphia, PA + 2 other US sites
- Eligibility basics
- Ages 8+ · Men only
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- Harrisburg, PA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- Camp Hill, PA + 16 other US sites
- Eligibility basics
- Ages 40–84
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Philadelphia, PA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Philadelphia, PA + 26 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Lancaster, PA + 25 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Pittsburgh, PA + 66 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- Pittsburgh, PA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Bridgeville, PA + 104 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Biosense Webster, Inc.
- Location
- Philadelphia, PA + 10 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- Pittsburgh, PA + 30 other US sites
- Eligibility basics
- Any age listed
- Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie Inc.
- Location
- Lancaster, PA + 33 other US sites
- Eligibility basics
- Ages 22–75
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Allentown, PA + 120 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
- Location
- Harrisburg, PA + 68 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.