Healthy volunteers · Massachusetts
Studies for healthy volunteers in Massachusetts
358 studies have at least one recruiting site in Massachusetts. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
358 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersEarly Phase 1
Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
Dana-Farber Cancer Institute
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Impulsivity Domains and Subjective Response
Jessica Weafer
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 21–25
- RecruitingHealthy volunteersEarly Phase 1
The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma
MCPHS University
- Location
- Worcester, MA
- Eligibility basics
- Ages 50–100
- RecruitingHealthy volunteersEarly Phase 1
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 40–99
- RecruitingHealthy volunteersOvernight stay mentioned
Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences
Boston Children's Hospital
- Location
- Boston, MA
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersPhase 1
Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Positron Emission Tomography (PET) Imaging of Thrombosis
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersEarly Phase 1
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
Beth Israel Deaconess Medical Center
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1/Phase 2
Molecular Imaging of NET Using [C-11]MRB-PET in MS
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1/Phase 2
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersEarly Phase 1
Assessment of Synaptic Density in MS
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersEarly Phase 1
Diffusion MRI in Heart Failure
Massachusetts General Hospital
- Location
- Charlestown, MA
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersEarly Phase 1
PET Imaging Evaluation of [11C]SY08
Massachusetts General Hospital
- Location
- Charlestown, MA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteersOvernight stay mentioned
Dietary Intervention to Mitigate Adverse Consequences of Night Work
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersEarly Phase 1
An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus
D. Bradley Welling, MD, PhD
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
Massachusetts Eye and Ear Infirmary
- Location
- Boston, MA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Assess Fibrin in Brains With AD/ADRD
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 55–90
- RecruitingHealthy volunteersEarly Phase 1
Mapping Auricular Vagus Nerve Circuitry
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Benjamin Medoff
- Location
- Boston, MA
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in…
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteers
The Impact of Overnight Active Temperature Regulation on Gut Microbiome, Inflammation, and Circadian Rhythm.
Eight Sleep Inc.
- Location
- Newton Center, MA
- Eligibility basics
- Ages 45+
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Methuen, MA + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteersPhase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Pfizer
- Location
- Boston, MA + 76 other US sites
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- West Roxbury, MA + 138 other US sites
- Eligibility basics
- Ages 65+
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.