Mental health · Massachusetts
Mental health studies in Massachusetts
84 studies have at least one recruiting site in Massachusetts. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
84 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
- Location
- Boston, MA + 31 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software
AugMend Health Inc.
- Location
- Cambridge, MA
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of ALTO-101 in Patients With Schizophrenia
Alto Neuroscience
- Location
- Belmont, MA + 12 other US sites
- Eligibility basics
- Ages 21–55
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Boston, MA + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Preventing Depression of Chinese American Adolescents by RRE
Northeastern University
- Location
- Boston, MA
- Eligibility basics
- Ages 14–18
- RecruitingHealthy volunteers
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
Massachusetts General Hospital
- Location
- Charlestown, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Project EMPOWER-OCD
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program
Boston University Charles River Campus
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 14+
- RecruitingHealthy volunteers
Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteers
Neuromodulation for a Novel OCD Biomarker and Treatment
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study
Beth Israel Deaconess Medical Center
- Location
- Boston, MA
- Eligibility basics
- Ages 15–18
- RecruitingHealthy volunteers
Neural Mechanisms of Family-Focused Treatment for Youth Depression
Boston University Charles River Campus
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 7–12
- RecruitingHealthy volunteers
Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
Massachusetts General Hospital
- Location
- Charlestown, MA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteers
Resilient Families Feasibility Trial
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Social Needs Screening and Chronic Diseases Study (WE CARE)
University of Massachusetts, Worcester
- Location
- Worcester, MA
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Mclean Hospital
- Location
- Belmont, MA
- Eligibility basics
- Ages 14–18 · Women only
- RecruitingHealthy volunteersPhase 2
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
Mclean Hospital
- Location
- Belmont, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
Sarah Schlegel
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Music Use in Parturients Admitted to Labor & Delivery
Tufts Medical Center
- Location
- Boston, MA
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder
Stony Brook University
- Location
- Belmont, MA + 1 other US site
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans
VA Office of Research and Development
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.