Mental health · Missouri
Mental health studies in Missouri
44 studies have at least one recruiting site in Missouri. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
44 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
Alkermes, Inc.
- Location
- Saint Charles, MO + 14 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
AbbVie
- Location
- Saint Charles, MO + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia
Novartis Pharmaceuticals
- Location
- St Louis, MO + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia
LB Pharmaceuticals Inc.
- Location
- St Louis, MO + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
LB Pharmaceuticals Inc.
- Location
- St Louis, MO + 25 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- O'Fallon, MO + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Bristol-Myers Squibb
- Location
- St Louis, MO + 19 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- O'Fallon, MO + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- St Louis, MO + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Saint Charles, MO + 33 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Brain Stimulation for Severe Depression
Inner Cosmos Inc
- Location
- St Louis, MO
- Eligibility basics
- Ages 21–80
- RecruitingPhase 2
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
VistaGen Therapeutics, Inc.
- Location
- Saint Charles, MO + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
- Location
- Saint Charles, MO + 31 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Randomized Withdrawal Study in Patients With Schizophrenia
Vanda Pharmaceuticals
- Location
- Saint Charles, MO + 21 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Saint Charles, MO + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1
Washington University School of Medicine
- Location
- St Louis, MO + 4 other US sites
- Eligibility basics
- Ages 18–59
- RecruitingHealthy volunteers
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 12–20
- RecruitingHealthy volunteers
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 10+ · Women only
- RecruitingHealthy volunteers
PTSD Screening in Pregnant Black Women
Emory University
- Location
- Kansas City, MO + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
University of Virginia
- Location
- Columbia, MO + 2 other US sites
- Eligibility basics
- Ages 10–99
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.