Phase 1 · Rochester, MN
Phase 1 clinical trials in Rochester, MN
34 recruiting studies have a site in Rochester.
34 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
Atavistik Bio, Inc
- Location
- Rochester, MN + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
A Study of Niacin Regulation
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Regional Lipolysis Insulin Regulation
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Insulin Regulation of Lipolysis and Lipolysis Proteins
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- Rochester, MN + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 1/Phase 2
Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease
CRISPR Therapeutics AG
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- Rochester, MN + 16 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)
Arbor Biotechnologies
- Location
- Rochester, MN
- Eligibility basics
- Ages 6–64
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- Rochester, MN + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
AstraZeneca
- Location
- Rochester, MN + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Eli Lilly and Company
- Location
- Rochester, MN + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Rocket Pharmaceuticals Inc.
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)
AAVantgarde Bio Srl
- Location
- Rochester, MN + 7 other US sites
- Eligibility basics
- Ages 8–55
- RecruitingPhase 1
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease
Merida Biosciences
- Location
- Rochester, MN + 10 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Solid Biosciences Inc.
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 7+
- RecruitingPhase 1/Phase 2
A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc.
- Location
- Rochester, MN + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X, Inc.
- Location
- Rochester, MN + 7 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis
Regeneron Pharmaceuticals
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1
Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement
Harvard Apparatus Regenerative Technology, Inc.
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome
Ionis Pharmaceuticals, Inc.
- Location
- Rochester, MN + 4 other US sites
- Eligibility basics
- Ages 2–12
- RecruitingPhase 1/Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Nuevocor Pte. Ltd.
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Alexion Pharmaceuticals, Inc.
- Location
- Rochester, MN + 9 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.