Phase 1 · Ohio
Phase 1 clinical trials in Ohio
83 studies have at least one recruiting site in Ohio. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
83 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- Cleveland, OH + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
U: The Mind Company
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
Treatment of Moderate to Severe Refractory Crohn's Disease
Tr1X, Inc.
- Location
- Cleveland, OH + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A proof-of Concept Study to Assess Safety and Tolerability of HM15421/GC1134A in Patients With Fabry Disease
GC Biopharma Corp
- Location
- Cincinnati, OH + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
PharmaIN
- Location
- Cleveland, OH + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant
Eledon Pharmaceuticals
- Location
- Cincinnati, OH
- Eligibility basics
- Ages 18–100
- RecruitingPhase 1
BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
Luminary Therapeutics
- Location
- Columbus, OH
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Canton, OH + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy
Sardocor Corp.
- Location
- Cincinnati, OH + 2 other US sites
- Eligibility basics
- Ages 18+ · Men only
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- Cleveland, OH + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
Telios Pharma, Inc.
- Location
- Canton, OH + 3 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.