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American Lung Association (ALA) Lung Health Cohort

Johns Hopkins University · with National Heart, Lung, and Blood Institute (NHLBI), American Lung Association · NCT04543461

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 25–35 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
4000
US sites recruiting
27
Study start
October 29, 2021
Record last updated
September 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.

Conditions: Lung Diseases

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

1- Age 25-35 years at the time of the baseline examination 2- Able to read and understand English or Spanish 3 -Has a social security number 4- Resident (citizen or non-citizen) of the United States (US) for at least 12 months prior to examination. Note: Individuals who are residents of the US who have temporarily spent time living outside of the US during the last 12 months (e.g., student exchange program, military posting) are eligible for participation.

5- Willing to provide contact information for at least 2 proxies who are likely to know the whereabouts and vital status of the participant

Exclusion Criteria

  • Severe asthma, which is defined as any of the following:
  • Current (i.e. at the time of the visit) GINA Step 4 or higher therapy (medium dose ICS/LABA or high dose ICS or add-on LAMA; Medium dose = >250 fluticasone, propionate =100 fluticasone furoate, >200 beclomethasone, >400 budesonide, >220 mometasone). We will accept low-dose ICS/LABA or medium dose ICS.

OR

  • 3 or more unscheduled healthcare visits (provider/urgent care/ER) for asthma in the past 12 months OR
  • One asthma hospitalization in the past 12 months
  • History of any chronic lung disease other than asthma including but not limited to COPD, cystic fibrosis, pulmonary fibrosis, pulmonary hypertension
  • Current pregnancy
  • History of cancer other than non-melanoma skin cancer
  • Diagnosed cardiovascular diseases (i.e., congenital heart disease, coronary heart disease)
  • Inability to comply with study procedures, including
  • Inability or unwillingness to provide informed consent
  • Inability to perform study measurements
  • Inability to be contacted by phone (via calls and/or text messaging) or email
  • Any condition in the opinion of the physician that puts the participant at risk by participating in the study (e.g., serious respiratory illness requiring antibiotics or steroids or severe fever at the time of the study visit).
  • Institutionalization

Recruiting US locations

  • University Of Alabama

    Birmingham, AL 35294

    Site contact: Necole Harris · 205-934-9240 · itis-lhc@uab.edu

  • University of Arizona-Tuscon

    Tucson, AZ 85724

    Site contact: Alyssandra Rivera · 520-626-6387 · arivera59@arizona.edu

  • University of California, Los Angeles

    Los Angeles, CA 90095

    Site contact: Tiffany Bina · 310-206-1629 · tbina@mednet.ucla.edu

  • University of California, San Francisco

    San Francisco, CA 94143

    Site contact: Shannen Recio · 415-203-8234 · shannen.recio@ucsf.edu

  • National Jewish Health

    Denver, CO 80206

    Site contact: Juno Pak · 303-398-1443 · PakJ@NJHealth.org

  • Nemours Children's Jacksonville

    Jacksonville, FL 32207

    Site contact: Micheal Littlefield · 904-697-3925 · Biomedicalresearch@nemours.org

  • University of Florida, Jacksonville

    Jacksonville, FL 32209

    Site contact: Jennifer Bowman · 904-244-1106 · Jennifer.Bowman@jax.ufl.edu

  • University of Illinois at Chicago

    Chicago, IL 60608

    Site contact: Lourdes Norwick · 312-413-5453 · lhc_study@uic.edu

  • Northwestern University

    Chicago, IL 60611

    Site contact: Shafic Kakooza · 312-503-6378 · lhc@northwestern.edu

  • Rush Universtiy

    Chicago, IL 60612

    Site contact: Jessica Parumoottil · 312-563-2168 · Jessica_Parumoottil@rush.edu

  • University of Iowa

    Iowa City, IA 52242

    Site contact: Eric Garcia · 319-353-8862 · eric-garcia@uiowa.edu

  • University of Kansas

    Kansas City, KS 66103

    Site contact: Nicole Hall · 913-588-1987 · nhall@kumc.edu

  • Johns Hopkins University

    Baltimore, MD 21218

    Site contact: Molly Lauver · 410-550-2863 · mlauver3@jhmi.edu

  • University of Michigan

    Ann Arbor, MI 48109

    Site contact: Wendy Warshal · 734-232-2841 · warshal@med.umich.edu

  • New York Medical College

    Hawthorne, NY 10532

    Site contact: Zachary Messer · 914-593-8904 · zachary_messer@nymc.edu

  • Mt. Sinai, NYC

    New York, NY 10029

    Site contact: Maria Wong · 212-241-2779 · mariaantonia.wong@mssm.edu

  • Cornell University

    New York, NY 10032

    Site contact: Alicia Morris, MS · 646-962-2741 · ajm2017@med.cornell.edu

  • University of Rochester

    Rochester, NY 14642

    Site contact: 585-369-6769 · LHC@URMC.Rochester.edu

  • Duke University

    Durham, NC 27710

    Site contact: Kaitlin Foy · 919-479-0861 · DukeAirwayResearch@duke.edu

  • Wake Forest School of Medicine

    Winston-Salem, NC 27104

    Site contact: Isaac Deaton · 336-713-8550 · ideaton@wakehealth.edu

  • Ohio State University

    Columbus, OH 43210

    Site contact: Joseph Santiago · 614-293-4925 · Joseph.Santiago@osumc.edu

  • Temple University

    Philadelphia, PA 19140

    Site contact: Sally Quinn · 215-707-1359 · breathe@tuhs.temple.edu

  • University of Pittsburg-Emphysema/COPD Research Center

    Pittsburgh, PA 15213

    Site contact: Tiffany Ditter · 412-648-6495 · dittertl2@upmc.edu

  • Medical University of South Carolina

    Charleston, SC 29425

    Site contact: Kristin Neff · 843-792-1219 · neffk@musc.edu

  • Vanderbilt University Medical Center

    Nashville, TN 37235

    Site contact: Courtney Lehman · 615-421-8172 · courtney.a.lehman@vumc.org

  • Baylor College of Medicine

    Houston, TX 77030

    Site contact: Laura Bertrand · 713-798-2681 · Laura.Bertrand@bcm.edu

  • University of Vermont

    Colchester, VT 05446

    Site contact: Grahm Janson · 802-847-2193 · Graham.Janson@uvmhealth.org

Study contacts (from the official record)

  • Elizabeth Sugar, PhD · 443-287-3170 · esugar2@jhu.edu
  • Curt Reynolds, MAS · 410-614-2422 · creynol1@jhu.edu
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American Lung Association (ALA) Lung Health Cohort (NCT04543461) | Bored Studies