Older adults · California
Studies for adults 50 and older in California
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
117 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in…
Apellis Pharmaceuticals, Inc.
- Location
- Bakersfield, CA + 77 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Beverly Hills, CA + 29 other US sites
- Eligibility basics
- Ages 50–80
- Recruiting
Preventing Medication Mismanagement in People Living With Dementia
HiDO Technologies
- Location
- Folsom, CA
- Eligibility basics
- Ages 65+
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Los Angeles, CA + 49 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1/Phase 2
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Luxa Biotechnology, LLC
- Location
- Beverly Hills, CA + 2 other US sites
- Eligibility basics
- Ages 55+
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Loma Linda, CA + 9 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 2
Ongoing Lung Decline With Age Intensified Response
Cedars-Sinai Medical Center
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Glaucoma Screening to Enhance At-Risk Californians' Health
University of California, San Francisco
- Location
- Fremont, CA + 1 other US site
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
Scott Silveira
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 60–80
- RecruitingHealthy volunteersPhase 3
Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
University of Alberta
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 50–70 · Men only
- RecruitingHealthy volunteers
Predicting Pre-dementia
Prevention Research Consortium Corp.
- Location
- San Diego, CA
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 4
Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPH
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 60+ · Women only
- RecruitingHealthy volunteers
Targeting Aging With a Ketone Ester for Function in Frailty
Buck Institute for Research on Aging
- Location
- Novato, CA + 2 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 4
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
- Location
- Fresno, CA + 88 other US sites
- Eligibility basics
- Ages 75+
- RecruitingHealthy volunteers
Enhancing Attention and Wellbeing Using Digital Therapeutics
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 60–99
- RecruitingHealthy volunteers
Measurement and Determinants of Diet Quality in Older Adults
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 2
Senicapoc in Alzheimer's Disease
University of California, Davis
- Location
- Sacramento, CA + 1 other US site
- Eligibility basics
- Ages 55–85
- RecruitingHealthy volunteers
Evaluating the Impact of CONNECT in a Multilingual Population
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
Kaiser Permanente
- Location
- Oakland, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Effect of Daily Mixed Spice Consumption on Memory Function
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Effects of Goji vs. Fiber on Macular Degeneration
University of California, Davis
- Location
- Sacramento, CA
- Eligibility basics
- Ages 65–95
- RecruitingHealthy volunteers
Sodium in the Skin and Atopic Dermatitis
University of California, San Francisco
- Location
- San Francisco, CA + 1 other US site
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy
City of Hope Medical Center
- Location
- Duarte, CA + 1 other US site
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Polyphenols and Cognitive Decline
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 50+