Older adults · Pennsylvania
Studies for adults 50 and older in Pennsylvania
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
45 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
ONL Therapeutics
- Location
- Erie, PA + 55 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
Dompé Farmaceutici S.p.A
- Location
- Philadelphia, PA + 13 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 1
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Astellas Institute for Regenerative Medicine
- Location
- Philadelphia, PA + 12 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Bethlehem, PA + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration
Kriya Therapeutics, Inc.
- Location
- Erie, PA
- Eligibility basics
- Ages 55–80
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
EyeBiotech Ltd.
- Location
- Erie, PA + 51 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Philadelphia, PA + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in…
Apellis Pharmaceuticals, Inc.
- Location
- Kingston, PA + 77 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Philadelphia, PA + 29 other US sites
- Eligibility basics
- Ages 50–80
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Pittsburgh, PA + 49 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1
Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
Caregen Co. Ltd.
- Location
- Erie, PA + 6 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)
University of Pennsylvania
- Location
- Philadelphia, PA + 1 other US site
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 4
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
- Location
- Pittsburgh, PA + 88 other US sites
- Eligibility basics
- Ages 75+
- RecruitingHealthy volunteers
Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity
University of Pittsburgh
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 75+ · Women only
- RecruitingHealthy volunteers
Thirst for Knowledge
Duquesne University
- Location
- Cornwall, PA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking
Ronald Myers
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 50–77
- RecruitingHealthy volunteers
Caregiver Stress and Sleep Study
University of Pittsburgh
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
Late Onset Alzheimer's Disease
Columbia University
- Location
- Pittsburgh, PA + 11 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 2
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
Johns Hopkins University
- Location
- Philadelphia, PA + 1 other US site
- Eligibility basics
- Ages 50–90
- RecruitingHealthy volunteers
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
University of Wisconsin, Madison
- Location
- Erie, PA + 6 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Temple Health Chest Initiative (THCI 2.0)
Temple University
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 50–80