Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease
Merida Biosciences
- Location
- Boston, MA + 10 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
RAPA-501 Therapy for ALS
Rapa Therapeutics LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
UCB Biopharma SRL
- Location
- Boston, MA + 41 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
Atsena Therapeutics Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 5+
- RecruitingPhase 3
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Vedanta Biosciences, Inc.
- Location
- Boston, MA + 55 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Intra-Cellular Therapies, Inc.
- Location
- Boston, MA + 22 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
Regeneron Pharmaceuticals
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 6 mo–6
- RecruitingPhase 2
Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)
Mirum Pharmaceuticals, Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 13–45 · Men only
- RecruitingPhase 2/Phase 3
Nectero EAST System Clinical Study
Nectero Medical, Inc.
- Location
- Boston, MA + 35 other US sites
- Eligibility basics
- Ages 21–85
- RecruitingPhase 3
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
Octapharma
- Location
- Boston, MA + 8 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- North Worcester, MA + 58 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 2
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Novartis Pharmaceuticals
- Location
- Brighton, MA + 22 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Waltham, MA + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Waltham, MA + 82 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
SAINT in Postpartum Depression (PPD)
Magnus Medical
- Location
- Worcester, MA + 3 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited
- Location
- Brookline, MA + 16 other US sites
- Eligibility basics
- Ages 3–12
- RecruitingPhase 2/Phase 3
Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
- Location
- Quincy, MA + 3 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 2
Effect of Patiromer in Children Under 12 Years of Age With High Blood Potassium Levels
Vifor Pharma, Inc.
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 0 mo–11
- RecruitingPhase 3
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Janssen Research & Development, LLC
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Boston, MA + 8 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
INHANCE Stemless Reverse Shoulder IDE
DePuy Orthopaedics
- Location
- Waltham, MA + 13 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
AbbVie
- Location
- New Bedford, MA + 53 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Janssen Research & Development, LLC
- Location
- Watertown, MA + 41 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Intra-Cellular Therapies, Inc.
- Location
- Worcester, MA + 27 other US sites
- Eligibility basics
- Ages 5–17