Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Boston, MA + 104 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
FIBERGRAFT Aeridyan Posterolateral Fusion Study
DePuy Synthes Products, Inc.
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Boston, MA + 44 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Janssen Research & Development, LLC
- Location
- Foxborough, MA + 14 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 3
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Boston, MA + 18 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Regeneron Pharmaceuticals
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- New Bedford, MA + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis
TearSolutions, Inc.
- Location
- Russells Mills, MA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Tonix Pharmaceuticals, Inc.
- Location
- Methuen, MA + 25 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- Boston, MA + 30 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic…
AstraZeneca
- Location
- Boston, MA + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Vanda Pharmaceuticals
- Location
- Boston, MA + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Solid Biosciences Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 7+
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Boston, MA + 120 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
Granata Bio Corporation
- Location
- Waltham, MA + 14 other US sites
- Eligibility basics
- Ages 18–42 · Women only
- RecruitingPhase 1/Phase 2
A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc.
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
argenx
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
Enveda Therapeutics
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- New Bedford, MA + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Insmed Gene Therapy LLC
- Location
- Worcester, MA + 6 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1
Study of GS-0415 and How It Works in People With HIV
Gilead Sciences
- Location
- Boston, MA + 14 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Belmont, MA + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)
Sanofi
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 1–18