Location · Minnesota
Clinical trials recruiting in Minnesota
563 recruiting studies have at least one site in Minnesota; 223 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Minnesota.
563 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Medtronic Cardiovascular
- Location
- Minneapolis, MN + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis
TearSolutions, Inc.
- Location
- Minneapolis, MN + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Pfizer
- Location
- Rochester, MN + 69 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 1/Phase 2
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease
UniQure Biopharma B.V.
- Location
- Minneapolis, MN + 9 other US sites
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingPhase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis
Azafaros B.V.
- Location
- Minneapolis, MN + 4 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 1
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Solid Biosciences Inc.
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 7+
- RecruitingPhase 1/Phase 2
A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc.
- Location
- Rochester, MN + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa
Oruka Therapeutics, Inc.
- Location
- New Brighton, MN + 13 other US sites
- Eligibility basics
- Ages 18–79
- Recruiting
Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
Echosens
- Location
- Minneota, MN + 2 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Hydrus® Microstent New Enrollment Post-Approval Study
Alcon Research
- Location
- Coon Rapids, MN + 12 other US sites
- Eligibility basics
- Ages 45+
- Recruiting
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Axon Therapies, Inc.
- Location
- Rochester, MN + 15 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
TVMR With the INNOVALVE System Trial - Early Feasibility Study
Edwards Lifesciences
- Location
- Rochester, MN + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
CSL Behring
- Location
- Minneapolis, MN + 147 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)
VDyne, Inc.
- Location
- Rochester, MN + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Takeda
- Location
- Plymouth, MN + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
Evaluation of the Efficacy and Safety of THRV-1268 in Participants With Long QT Syndrome Type 2 (LQTS2) and Type 3 (LQTS3)
Thryv Therapeutics, Inc.
- Location
- Rochester, MN + 6 other US sites
- Eligibility basics
- Ages 15+
- RecruitingPhase 1/Phase 2
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X, Inc.
- Location
- Rochester, MN + 7 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Vertex Pharmaceuticals Incorporated
- Location
- Edina, MN + 26 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
JenaValve Technology, Inc.
- Location
- Minneapolis, MN + 33 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Novo Nordisk A/S
- Location
- Minneapolis, MN + 42 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)
Vaderis Therapeutics AG
- Location
- Rochester, MN + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Mankato, MN + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old
Neurocrine Switzerland GmbH
- Location
- Minneapolis, MN + 10 other US sites
- Eligibility basics
- Ages 4 mo–3
- Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
- Location
- Minneapolis, MN + 68 other US sites
- Eligibility basics
- Ages 18+