Location · Pennsylvania
Clinical trials recruiting in Pennsylvania
943 recruiting studies have at least one site in Pennsylvania; 330 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Pennsylvania.
943 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Eli Lilly and Company
- Location
- Scottdale, PA + 24 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Tempus AI
- Location
- Philadelphia, PA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals
- Location
- Pittsburgh, PA + 8 other US sites
- Eligibility basics
- Ages 2–100
- RecruitingPhase 2
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC
- Location
- Pittsburgh, PA + 9 other US sites
- Eligibility basics
- Ages 30+
- RecruitingPhase 2
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Incyte Corporation
- Location
- Danville, PA + 23 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Genentech, Inc.
- Location
- Erie, PA + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis
UCB Biopharma SRL
- Location
- DuBois, PA + 6 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma
Pfizer
- Location
- Pittsburgh, PA + 1 other US site
- Eligibility basics
- Ages 12–80
- Recruiting
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
W.L.Gore & Associates
- Location
- Sayre, PA + 20 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 2
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
Regeneron Pharmaceuticals
- Location
- Danville, PA + 34 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
- Location
- Philadelphia, PA + 44 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis
Molecure S.A.
- Location
- Philadelphia, PA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pegtibatinase as a Treatment for Participants With Classical Homocystinuria (HCU) Receiving Standard of Care Treatment
Travere Therapeutics, Inc.
- Location
- Philadelphia, PA + 11 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1/Phase 2
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Ionis Pharmaceuticals, Inc.
- Location
- Philadelphia, PA + 7 other US sites
- Eligibility basics
- Ages 2–65 · Men only
- Recruiting
The PERSEVERE Study
Inari Medical
- Location
- Philadelphia, PA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
CSL Behring
- Location
- Pittsburgh, PA + 18 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Duncansville, PA + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Bristol-Myers Squibb
- Location
- Plymouth Meeting, PA + 22 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
AllRock Bio, Inc.
- Location
- Philadelphia, PA + 10 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Eli Lilly and Company
- Location
- Erie, PA + 17 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Eli Lilly and Company
- Location
- Camp Hill, PA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
Regeneron Pharmaceuticals
- Location
- Bethlehem, PA + 55 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
- Location
- Pittsburgh, PA + 59 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Plymouth Meeting, PA + 37 other US sites
- Eligibility basics
- Ages 18+