Heart & blood pressure · North Carolina
Heart and blood pressure studies in North Carolina
90 studies have at least one recruiting site in North Carolina. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
90 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.
XyloCor Therapeutics, Inc.
- Location
- Durham, NC + 12 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
BrioHealth Solutions, Inc.
- Location
- Durham, NC + 46 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- High Point, NC + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Pulmovant, Inc.
- Location
- Greensboro, NC + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
EmStop Inc
- Location
- Asheville, NC + 6 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
- Location
- Charlotte, NC + 31 other US sites
- Eligibility basics
- Ages 21+
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Asheville, NC + 42 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- Durham, NC + 39 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
FORWARD CAD IDE Study
Shockwave Medical, Inc.
- Location
- Raleigh, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Immunovant Sciences GmbH
- Location
- Chapel Hill, NC + 47 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Monroe, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- Monroe, NC + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Study of CRD-4730 in CPVT
Cardurion Pharmaceuticals, Inc.
- Location
- Morrisville, NC + 4 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
AquaPass Medical Ltd.
- Location
- Asheville, NC + 7 other US sites
- Eligibility basics
- Ages 21–79
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Durham, NC + 46 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Durham, NC + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Winston-Salem, NC + 29 other US sites
- Eligibility basics
- Ages 50–80
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Chapel Hill, NC + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- Charlotte, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Durham, NC + 36 other US sites
- Eligibility basics
- Ages 18–90
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Kinston, NC + 17 other US sites
- Eligibility basics
- Ages 18–65
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.