Arthritis · North Carolina
Arthritis studies in North Carolina
26 studies have at least one recruiting site in North Carolina. Arthritis studies include osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout and ankylosing spondylitis.
26 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersOvernight stay mentioned
The Osteoarthritis Prevention Study
Wake Forest University
- Location
- Winston-Salem, NC + 1 other US site
- Eligibility basics
- Ages 50+ · Women only
- RecruitingPhase 3
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
Medipost, Inc.
- Location
- Charlotte, NC + 33 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With…
Amgen
- Location
- Charlotte, NC + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Takeda
- Location
- Hickory, NC + 45 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
Novartis Pharmaceuticals
- Location
- Charlotte, NC + 10 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Charlotte, NC + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Charlotte, NC + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Charlotte, NC + 82 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
Crystalys Therapeutics
- Location
- Charlotte, NC + 40 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))
DePuy Orthopaedics
- Location
- Gastonia, NC + 1 other US site
- Eligibility basics
- Ages 21+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Charlotte, NC + 20 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Charlotte, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
- Location
- Chapel Hill, NC + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
AbbVie
- Location
- Chapel Hill, NC + 11 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Statesville, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Charlotte, NC + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Artiva Biotherapeutics, Inc.
- Location
- Charlotte, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
MISHA Post-Market Clinical Study
Moximed
- Location
- Raleigh, NC + 3 other US sites
- Eligibility basics
- Ages 25–65
- RecruitingPhase 1
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
Clinical Outcomes Study of the Nexel Total Elbow
Zimmer Biomet
- Location
- Charlotte, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Wilmington, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Drug-Drug Interaction Study of ABP-671 in Gout Patients
Atom Therapeutics Co., Ltd
- Location
- Cary, NC
- Eligibility basics
- Ages 18–75
- Recruiting
Knee Biofeedback Rehabilitation Through Game Therapy
Barron Associates, Inc.
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 30–75
Who these studies look for
Most require a confirmed diagnosis, often with X-rays or blood tests, and set rules for pain medicines during the study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I keep taking my pain medicine?
Some studies allow it, some require a washout period first. The study team will explain the rules before you agree to anything.