Smoking & vaping · North Carolina
Smoking and vaping studies in North Carolina
8 studies have at least one recruiting site in North Carolina. Tobacco research includes quit-smoking and quit-vaping programs, new cessation medicines and studies of how nicotine products affect the body.
8 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersEarly Phase 1
Cardiovascular Effects of Very Low Nicotine Content Cigarettes
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersEarly Phase 1
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–21
- RecruitingHealthy volunteers
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
RAI Services Company
- Location
- Raleigh, NC + 6 other US sites
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54
Wake Forest University Health Sciences
- Location
- Charlotte, NC
- Eligibility basics
- Ages 40–54
- RecruitingHealthy volunteers
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 4
Woodsmoke Exposure, Influenza Infection, and Nasal Immunity
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18–49
- RecruitingHealthy volunteersPhase 2/Phase 3
Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology
Y. Michael Shim, MD
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteers
Take A Break - Rural
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+
Who these studies look for
Most require current smoking or vaping at a set level, measured at screening. Quit studies often include counseling.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do I have to quit to join?
Cessation studies are for people who want to quit. Other tobacco studies may ask you to keep your usual habits or switch products for a period. The listing explains which.