Study type
Heart and blood pressure studies recruiting now
Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
494 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Medtronic Terminate AF Study
Medtronic Cardiac Surgery
- Location
- Indianapolis, IN + 6 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis
Dermed Diagnostics, Inc.
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Merck Sharp & Dohme LLC
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- La Jolla, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
Amgen
- Location
- Bridgeport, CT + 5 other US sites
- Eligibility basics
- Ages 35–80
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- Gilbert, AZ + 50 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
Aktiia SA
- Location
- Boston, MA
- Eligibility basics
- Ages 21–85
- RecruitingPhase 2
Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels
NewAmsterdam Pharma
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–75
- Recruiting
STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)
MiRus
- Location
- Atlanta, GA
- Eligibility basics
- Ages 18+
- Recruiting
Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD
SeaStar Medical
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Glaukos Corporation
- Location
- Dothan, AL
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Tucson, AZ + 36 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- La Jolla, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- La Jolla, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study
Vektor Medical
- Location
- Jonesboro, AR + 9 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Tempe, AZ + 17 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
Aventyn, Inc.
- Location
- Gilbert, AZ + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction
BioCardia, Inc.
- Location
- Clearwater, FL + 3 other US sites
- Eligibility basics
- Ages 21–90
- RecruitingPhase 2
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
Abcentra
- Location
- Torrance, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
Glaukos Corporation
- Location
- Kenosha, WI
- Eligibility basics
- Ages 45+
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Huntsville, AL + 49 other US sites
- Eligibility basics
- Ages 65+
- Recruiting
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
EnCompass Technologies, Inc.
- Location
- Indianappolis, IN + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Marea Therapeutics
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Phoenix, AZ + 34 other US sites
- Eligibility basics
- Ages 12–18
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.