Study type
Heart and blood pressure studies recruiting now
Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
494 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Trial of CRD-4730 in HFrEF
Cardurion Pharmaceuticals, Inc.
- Location
- Pasadena, CA + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- La Jolla, CA + 39 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
FORWARD CAD IDE Study
Shockwave Medical, Inc.
- Location
- La Jolla, CA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Immunovant Sciences GmbH
- Location
- Huntsville, AL + 47 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Garden Grove, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- Foley, AL + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
Eidos Therapeutics, a BridgeBio company
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 2–11
- Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
- Location
- Concord, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Zona Health, Inc
- Location
- Valley Village, CA + 9 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
The TRICURE EFS Study
TRiCares
- Location
- Atlanta, GA + 7 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation
Arga Medtech SA
- Location
- Birmingham, AL + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Birmingham, AL + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
A Phase 2 Study of CRD-4730 in CPVT
Cardurion Pharmaceuticals, Inc.
- Location
- San Francisco, CA + 4 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
AquaPass Medical Ltd.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 21–79
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Birmingham, AL + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
18F-mFBG Imaging for Myocardial Sympathetic Innervation
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)
- Location
- Houston, TX
- Eligibility basics
- Ages 18+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Phoenix, AZ + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Huntsville, AL + 29 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 3
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals
- Location
- Birmingham, AL + 112 other US sites
- Eligibility basics
- Ages 45+
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Phoenix, AZ + 56 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Applause Study I - Append System Early Feasibility Study
Append Medical Ltd.
- Location
- Jonesboro, AR + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- La Jolla, CA + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 6 other US sites
- Eligibility basics
- Ages 6–11
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.