Diabetes · North Carolina
Diabetes studies in North Carolina
53 studies have at least one recruiting site in North Carolina. Diabetes research covers type 1 and type 2 diabetes, prediabetes and related complications, testing medicines, devices such as glucose monitors and insulin pumps, and lifestyle programs.
53 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
- Location
- Chapel Hill, NC + 60 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Amgen
- Location
- Morehead City, NC + 30 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
Novo Nordisk A/S
- Location
- Greensboro, NC + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
AstraZeneca
- Location
- Statesville, NC + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Monroe, NC + 40 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1…
Aqua Medical, Inc.
- Location
- Chapel Hill, NC + 3 other US sites
- Eligibility basics
- Ages 22–65
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Raleigh, NC + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Durham, NC + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
Novo Nordisk A/S
- Location
- Greensboro, NC + 19 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
Samaritan Biologics
- Location
- Monroe, NC
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
AstraZeneca
- Location
- Raleigh, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Morehead City, NC + 55 other US sites
- Eligibility basics
- Ages 45+
- Recruiting
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
DreaMed Diabetes
- Location
- Morehead City, NC + 4 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Eli Lilly and Company
- Location
- Chapel Hill, NC + 39 other US sites
- Eligibility basics
- Ages 10–17
- Recruiting
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
Insulet Corporation
- Location
- Asheville, NC + 25 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Asheville, NC + 69 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
Zucara Therapeutics Inc.
- Location
- Morehead City, NC + 36 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Piomic Medical
- Location
- Chapel Hill, NC + 24 other US sites
- Eligibility basics
- Ages 22–90
- RecruitingPhase 4
A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL
HealthTech Wound Care
- Location
- Cary, NC + 9 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers
Zhuhai Rui-Inno Pharmaceutical Technology Co., Ltd.
- Location
- Durham, NC
- Eligibility basics
- Ages 18–75
- Recruiting
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
Tides Medical
- Location
- Raleigh, NC + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Intraoperative OCT Guidance of Intraocular Surgery II
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1 mo+
- RecruitingHealthy volunteers
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
Wake Forest Alzheimer's Disease Clinical Core
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 55+
Who these studies look for
Studies commonly set an HbA1c range, a diagnosis duration and a list of allowed or excluded medications. Some also recruit people without diabetes as a comparison group.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will I have to stop my diabetes medicine?
Some studies change or pause medicines under close supervision; many add a study treatment on top of your current care. Never change medicines on your own; the study team and your doctor decide this together.