Phase 1 · Florida
Phase 1 clinical trials in Florida
191 studies have at least one recruiting site in Florida. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
191 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
- Location
- Jacksonville, FL + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Sustained Acoustic Medicine for Osteoarthritis Pain
ZetrOZ, Inc.
- Location
- Tampa, FL
- Eligibility basics
- Ages 35–85
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Gainesville, FL + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2Overnight stay mentioned
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
Vector Y Therapeutics
- Location
- Jacksonville, FL + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1Overnight stay mentioned
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Novartis Pharmaceuticals
- Location
- Bradenton, FL + 4 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 1Overnight stay mentioned
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Leal Therapeutics, Inc
- Location
- DeLand, FL + 9 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1Overnight stay mentioned
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
BioXcel Therapeutics Inc
- Location
- Hialeah, FL + 3 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Up to age 50
- RecruitingHealthy volunteersEarly Phase 1
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
University of South Florida
- Location
- Tampa, FL
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Jacksonville, FL + 4 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersPhase 1/Phase 2
Retina is a Marker for Cerebrovascular Heath
Mayo Clinic
- Location
- Jacksonville, FL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 45–85
- RecruitingHealthy volunteersEarly Phase 1
Quadriceps Motor Unit Adaptation to Simulated Knee Injury
University of Central Florida
- Location
- Orlando, FL
- Eligibility basics
- Ages 18–30
- RecruitingHealthy volunteersPhase 1/Phase 2
Rh-PDGF vs EMD for Treatment of Intra-bony Defects
Nova Southeastern University
- Location
- Davie, FL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Intermittent Visual Perturbations to Enhance Balance Training
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 18–89
- RecruitingHealthy volunteersPhase 1/Phase 2
Linaclotide for Colonoscopy Bowel Prep
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 21–45
- RecruitingHealthy volunteersEarly Phase 1
Researching Economical Adjuvants to Cancer Therapy
Florida State University
- Location
- Tallahassee, FL
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1/Phase 2
Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
University of Miami
- Location
- Miami, FL
- Eligibility basics
- Ages 1–21
- RecruitingHealthy volunteersEarly Phase 1
Promoting Playfulness
Florida Gulf Coast University
- Location
- Fort Myers, FL
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- Miami, FL + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 1
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
Verve Therapeutics, Inc.
- Location
- Clearwater, FL + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC36 Tablets for Oral Use in Adult Participants With Obesity or Overweight
Ascletis Pharma (China) Co., Limited
- Location
- South Miami, FL
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics Inc.
- Location
- Orlando, FL + 10 other US sites
- Eligibility basics
- Ages 18–70
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.