Weight loss · Illinois
Weight loss and obesity studies in Illinois
46 studies have at least one recruiting site in Illinois. Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
46 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Hazel Crest, IL + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Chicago, IL + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Novo Nordisk A/S
- Location
- Chicago, IL + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Gurnee, IL + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Chicago, IL + 129 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Gurnee, IL + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
AbbVie
- Location
- Grayslake, IL + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Rhythm Pharmaceuticals, Inc.
- Location
- Chicago, IL + 7 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 2/Phase 3
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
AgelessRx
- Location
- Chicago, IL
- Eligibility basics
- Ages 40–85
- RecruitingHealthy volunteers
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
Midwest Center for Metabolic and Cardiovascular Research
- Location
- Addison, IL + 2 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingHealthy volunteers
A Novel Intervention for Weight Loss in Young Adults
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteers
Healthy Options At Pantries (HOAP) Study
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
BRIDGE & Friends Trial
University of Illinois at Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 50–79
- RecruitingHealthy volunteers
Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.
Midwest Center for Metabolic and Cardiovascular Research
- Location
- Chicago, IL
- Eligibility basics
- Ages 21–74
- RecruitingHealthy volunteers
EAT: A Reliable Eating Assessment Technology for Free-living Individuals
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Stable Isotopes- Adults With Obesity
University of Illinois at Urbana-Champaign
- Location
- Urbana, IL
- Eligibility basics
- Ages 19–59
- RecruitingHealthy volunteers
Exercise and Protein Efficiency in T2D
University of Illinois at Urbana-Champaign
- Location
- Urbana, IL
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
RemI for Post-Bariatric Surgery Weight Regain
Temple University
- Location
- Chicago, IL + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteers
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
Benjamin T. Miller
- Location
- Chicago, IL + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Predictors of Behavioral Obesity Treatment Outcomes
Rush University Medical Center
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
DNA Methylation and Vascular Function
University of Illinois at Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteers
INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY
University of Illinois at Urbana-Champaign
- Location
- Bloomington, IL
- Eligibility basics
- Ages 6–11
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.