Older adults · North Carolina
Studies for adults 50 and older in North Carolina
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
40 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Durham, NC + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Winston-Salem, NC + 29 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 2
Open-label Extension Study in Participants With Early Alzheimer's Disease
GlaxoSmithKline
- Location
- Matthews, NC + 8 other US sites
- Eligibility basics
- Ages 50–85
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Greensboro, NC + 49 other US sites
- Eligibility basics
- Ages 65+
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Asheville, NC + 9 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sardocor Corp.
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Wake Forest Alzheimer's Disease Clinical Core
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
Case Comprehensive Cancer Center
- Location
- Chapel Hill, NC + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 4
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
- Location
- Asheville, NC + 88 other US sites
- Eligibility basics
- Ages 75+
- RecruitingHealthy volunteers
Health Education Approach to Lung Screening
Virginia Commonwealth University
- Location
- Carrboro, NC + 2 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50–89
- RecruitingHealthy volunteers
Pain With Dementia
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Late Onset Alzheimer's Disease
Columbia University
- Location
- Raleigh, NC + 11 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 4
Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Cognition, Flavonoids, Exercise, Gut Microbiome
Appalachian State University
- Location
- Kannapolis, NC
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteers
Effect of Beet-root Juice and PBM Treatments on Muscle Fatigue
Wake Forest University
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 65+