Location · Illinois
Clinical trials recruiting in Illinois
890 recruiting studies have at least one site in Illinois; 285 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Illinois.
890 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
Incyte Corporation
- Location
- Chicago, IL + 36 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2/Phase 3
A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia
Alkermes, Inc.
- Location
- Peoria, IL + 32 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis
Zomagen Biosciences Ltd.
- Location
- Chicago, IL + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Incyte Corporation
- Location
- Chicago, IL + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)
Dianthus Therapeutics
- Location
- Chicago, IL + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
AstraZeneca
- Location
- Evanston, IL + 53 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Tempus AI
- Location
- Chicago, IL + 39 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ELEVATE High-Risk PCI Pivotal Study
Magenta Medical Ltd.
- Location
- Chicago, IL + 32 other US sites
- Eligibility basics
- Ages 18–88
- RecruitingPhase 2
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC
- Location
- Chicago, IL + 9 other US sites
- Eligibility basics
- Ages 30+
- RecruitingPhase 2
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Incyte Corporation
- Location
- Skokie, IL + 23 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
AstraZeneca
- Location
- Skokie, IL + 20 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
Tissium
- Location
- Chicago, IL + 7 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated…
Eccogene
- Location
- Glenview, IL + 65 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
AtaCor Medical, Inc.
- Location
- Glenview, IL + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis
UCB Biopharma SRL
- Location
- O'Fallon, IL + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's Ataxia
Larimar Therapeutics, Inc.
- Location
- Chicago, IL + 2 other US sites
- Eligibility basics
- Ages 12–40
- RecruitingPhase 3
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
- Location
- Springfield, IL + 44 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
- Location
- Springfield, IL + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pegtibatinase as a Treatment for Participants With Classical Homocystinuria (HCU) Receiving Standard of Care Treatment
Travere Therapeutics, Inc.
- Location
- Chicago, IL + 11 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 2
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
CSL Behring
- Location
- Chicago, IL + 18 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Chicago, IL + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Bristol-Myers Squibb
- Location
- Chicago, IL + 22 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Arlington Heights, IL + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 2
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Eli Lilly and Company
- Location
- Des Plaines, IL + 36 other US sites
- Eligibility basics
- Ages 18–80