Location · Illinois
Clinical trials recruiting in Illinois
890 recruiting studies have at least one site in Illinois; 285 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Illinois.
890 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Champaign, IL + 104 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
CorMedix Therapeutics
- Location
- Chicago, IL + 16 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 4
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
Neurotech Pharmaceuticals
- Location
- Chicago, IL + 15 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
FIBERGRAFT Aeridyan Posterolateral Fusion Study
DePuy Synthes Products, Inc.
- Location
- Chicago, IL + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Chicago, IL + 44 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Janssen Research & Development, LLC
- Location
- O'Fallon, IL + 14 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Evanston, IL + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Enveda Therapeutics
- Location
- Chicago, IL + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Willowbrook, IL + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Medtronic Cardiovascular
- Location
- Chicago, IL + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
AstraZeneca
- Location
- Willowbrook, IL + 14 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Janssen Research & Development, LLC
- Location
- Willowbrook, IL + 37 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Tonix Pharmaceuticals, Inc.
- Location
- Chicago, IL + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
Janssen Research & Development, LLC
- Location
- Skokie, IL + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Pfizer
- Location
- Chicago, IL + 69 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 3
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Pfizer
- Location
- Chicago, IL + 54 other US sites
- Eligibility basics
- Ages 6–17
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- Elk Grove Village, IL + 30 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease
UniQure Biopharma B.V.
- Location
- Chicago, IL + 9 other US sites
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic…
AstraZeneca
- Location
- Willowbrook, IL + 31 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie Inc.
- Location
- Elk Grove Village, IL + 33 other US sites
- Eligibility basics
- Ages 22–75
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Vanda Pharmaceuticals
- Location
- Chicago, IL + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Chicago, IL + 120 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
Granata Bio Corporation
- Location
- Chicago, IL + 14 other US sites
- Eligibility basics
- Ages 18–42 · Women only
- RecruitingPhase 2
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
Enveda Therapeutics
- Location
- Maryville, IL + 19 other US sites
- Eligibility basics
- Ages 18–75