Healthy volunteers · North Carolina
Studies for healthy volunteers in North Carolina
250 studies have at least one recruiting site in North Carolina. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
250 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Reproductive Axis Maturation in the Early Post-Menarchal Years
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC
- Eligibility basics
- Ages 8–65 · Women only
- RecruitingHealthy volunteers
Sugary Drink Labeling Study
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Mayo Clinic
- Location
- Chapel Hill, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)
National Alliance for Sickle Cell Centers
- Location
- Chapel Hill, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study
Wake Forest University Health Sciences
- Location
- Pinehurst, NC + 101 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Wake Forest Alzheimer's Disease Clinical Core
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 4
Prescription of Letrozole for Uterine Myoma
University of California, San Francisco
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 21–53 · Women only
- RecruitingHealthy volunteers
The Vanguard Study: Testing a New Way to Screen for Cancer
National Cancer Institute (NCI)
- Location
- Chapel Hill, NC + 44 other US sites
- Eligibility basics
- Ages 45–75
- RecruitingHealthy volunteers
Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC + 42 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
NASA Exercise Prebreathe Study
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 30–60
- RecruitingHealthy volunteers
Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteersPhase 2
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
Mayo Clinic
- Location
- Chapel Hill, NC + 3 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteers
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
Northwestern University
- Location
- Winston-Salem, NC + 5 other US sites
- Eligibility basics
- Ages 30+
- RecruitingHealthy volunteers
Immune Cell Response to Stimuli
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Neural Correlates of Real World Spatial Navigation in Humans
Duke University
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–90
- RecruitingHealthy volunteers
Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
UNC Lineberger Comprehensive Cancer Center
- Location
- Chapel Hill, NC
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Evaluation of a Health System Integrated Model for Postpartum Education and Support in Rural Populations
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Evaluation of Flexible Conductive Hearing Aids
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 6 mo–80
- RecruitingHealthy volunteers
Adult and Juvenile Myositis
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC + 1 other US site
- Eligibility basics
- Ages 2–100
- RecruitingHealthy volunteers
American Lung Association (ALA) Lung Health Cohort
Johns Hopkins University
- Location
- Durham, NC + 26 other US sites
- Eligibility basics
- Ages 25–35
- RecruitingHealthy volunteers
Leveraging Chatbot to Improve PrEP in the Southern United States
Yale University
- Location
- Charlotte, NC + 3 other US sites
- Eligibility basics
- Ages 18+ · Men only
- RecruitingHealthy volunteers
Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 8–13
- RecruitingHealthy volunteers
Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study
Case Western Reserve University
- Location
- Chapel Hill, NC + 2 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteersPhase 3
Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
VA Office of Research and Development
- Location
- Asheville, NC + 17 other US sites
- Eligibility basics
- Ages 18–80
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.