Healthy volunteers · North Carolina
Studies for healthy volunteers in North Carolina
250 studies have at least one recruiting site in North Carolina. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
250 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Comparing Two Acute Care Transition Programs for Older Adults and Their Family Caregivers
Wake Forest University Health Sciences
- Location
- Bermuda Run, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Personalized Environment and Genes Study
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Chapel Hill, NC + 1 other US site
- Eligibility basics
- Ages 18–120
- RecruitingHealthy volunteers
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
Case Comprehensive Cancer Center
- Location
- Chapel Hill, NC + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
COmmunities Aligned to Reduce Concussion and Head Impact Exposure
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 11–14
- RecruitingHealthy volunteers
Physical Activity to Mitigate PreEclampsia Risk
East Carolina University
- Location
- Greenville, NC
- Eligibility basics
- Ages 18–40 · Women only
- RecruitingHealthy volunteers
MAMA Tot - Healthy Weight Parallel Study
East Carolina University
- Location
- Greenville, NC
- Eligibility basics
- Ages 18–40 · Women only
- RecruitingHealthy volunteers
Stress and Menstrual Health
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 22–38 · Women only
- RecruitingHealthy volunteers
Comparing a Workplace Resilience and a Physical Activity Intervention on Early Childhood Educators Well-being
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteers
ADRC Clinical Cohort (Alzheimer's Disease)
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 25–80
- RecruitingHealthy volunteers
Daily Upgrade Trial
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 25–45 · Women only
- RecruitingHealthy volunteers
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer
UNC Lineberger Comprehensive Cancer Center
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
- Location
- Asheville, NC + 88 other US sites
- Eligibility basics
- Ages 75+
- RecruitingHealthy volunteers
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Duke University
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteers
Using PrEP, Doing It for Ourselves
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Duke APOL1 Research Biorepository
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
The HOPE Biobank Resource (BMT CTN 2402 HOPE)
Medical College of Wisconsin
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Health Education Approach to Lung Screening
Virginia Commonwealth University
- Location
- Carrboro, NC + 2 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
The SEQUENCE Trial
Northwestern University
- Location
- Chapel Hill, NC + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
ASSESS ALL ALS Study
St. Joseph's Hospital and Medical Center, Phoenix
- Location
- Durham, NC + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
PREVENT ALL ALS Study
St. Joseph's Hospital and Medical Center, Phoenix
- Location
- Durham, NC + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Safer Drinking Spaces Study
RTI International
- Location
- Durham, NC + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Effects of Flavonoid Foods on Carbonyl Stress
North Carolina Agriculture & Technical State University
- Location
- Kannapolis, NC
- Eligibility basics
- Ages 25–70
- RecruitingHealthy volunteers
Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn
North Carolina Agriculture & Technical State University
- Location
- Kannapolis, NC
- Eligibility basics
- Ages 25–70
- RecruitingHealthy volunteers
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Duke University
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 0 mo–20
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.