Healthy volunteers · North Carolina
Studies for healthy volunteers in North Carolina
250 studies have at least one recruiting site in North Carolina. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
250 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Stress Trajectories and Anhedonia in Adolescence Research Study
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 13–15
- RecruitingHealthy volunteers
Prototyping a Device for Automating Stool and Urine Output Tracking
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Neuromodulation of Memory in Aging
Indiana University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Case Western Reserve University
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50–89
- RecruitingHealthy volunteers
Robotic OCT for ER Anterior Eye Exams
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Optimize Pediatric OCT Imaging
Duke University
- Location
- Durham, NC
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Pain With Dementia
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
UNC Lineberger Comprehensive Cancer Center
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 6+
- RecruitingHealthy volunteers
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
American College of Radiology
- Location
- Greenville, NC + 10 other US sites
- Eligibility basics
- Ages 45–74 · Women only
- RecruitingHealthy volunteers
Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)
National Cancer Institute (NCI)
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Ages 25+ · Women only
- RecruitingHealthy volunteers
Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Reducing Risk for Infective Endocarditis
Wake Forest University Health Sciences
- Location
- Charlotte, NC + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
High Point University
- Location
- High Point, NC
- Eligibility basics
- Ages 18–30
- RecruitingHealthy volunteersPhase 2/Phase 3
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
University of Colorado, Denver
- Location
- Chapel Hill, NC + 2 other US sites
- Eligibility basics
- Ages 45–55 · Women only
- RecruitingHealthy volunteers
Deep Functional Phenotyping of the ALA Lung Health Cohort
Johns Hopkins University
- Location
- Durham, NC + 11 other US sites
- Eligibility basics
- Ages 25–35
- RecruitingHealthy volunteers
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
Cure HHT
- Location
- Chapel Hill, NC + 15 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54
Wake Forest University Health Sciences
- Location
- Charlotte, NC
- Eligibility basics
- Ages 40–54
- RecruitingHealthy volunteers
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Evaluation of the Pathobiology of CALR-mutated MPN Cells
Wake Forest University Health Sciences
- Location
- Charlotte, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study
Wake Forest University Health Sciences
- Location
- Charlotte, NC
- Eligibility basics
- Ages 30+
- RecruitingHealthy volunteers
Pre-malignant States to Hematologic Malignancies in Firefighters
Wake Forest University Health Sciences
- Location
- Charlotte, NC
- Eligibility basics
- Ages 40–49
- RecruitingHealthy volunteers
MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–45
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.