Core: healthy volunteers
Studies for healthy volunteers recruiting now
These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
5,002 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
Tracing the Metabolic Flux of Orally Administered NAD+ Precursors
Metro International Biotech, LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
- Location
- San Francisco, CA + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
General Biophysics LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 55–75
- RecruitingHealthy volunteersPhase 1
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
ZetrOZ, Inc.
- Location
- Trumbull, CT + 1 other US site
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Sustained Acoustic Medicine for Osteoarthritis Pain
ZetrOZ, Inc.
- Location
- Tampa, FL
- Eligibility basics
- Ages 35–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Spermatogonial Differentiation Via Testicular Organoid
CellARTs Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–60 · Men only
- RecruitingHealthy volunteersPhase 1
A Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Thomas Advanced Medical LLC
- Location
- Culver City, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 12–75
- RecruitingHealthy volunteersEarly Phase 1
Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
Roswell Park Cancer Institute
- Location
- Buffalo, NY
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersPhase 1
Environment and Alcohol: A Pilot Study
National Institute on Drug Abuse (NIDA)
- Location
- Baltimore, MD
- Eligibility basics
- Ages 21–100
- RecruitingHealthy volunteersPhase 1
Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
City of Hope Medical Center
- Location
- Duarte, CA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 50–100
- RecruitingHealthy volunteersPhase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Decatur, GA + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
National Institute on Aging (NIA)
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65–120
- RecruitingHealthy volunteersPhase 1
Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE4D Imaging in Healthy Volunteers
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–105
- RecruitingHealthy volunteersOvernight stay mentioned
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 0 mo–100
- RecruitingHealthy volunteersPhase 1
Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
SV2A in Older Adults
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersOvernight stay mentioned
Eating to Adjust the Timing System
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.