Weight loss · Boston area, MA
Weight loss and obesity studies in Boston area, MA
20 recruiting studies have a site in the Boston area. This page includes nearby cities such as Cambridge, Brookline, Newton, Waltham.
20 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersOvernight stay mentioned
The Osteoarthritis Prevention Study
Wake Forest University
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 50+ · Women only
- Recruiting
The RESET System Pivotal Clinical Trial (Protocol Revision K)
Morphic Medical Inc.
- Location
- Boston, MA + 25 other US sites
- Eligibility basics
- Ages 22–65
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Hoffmann-La Roche
- Location
- Boston, MA + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Boston, MA + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Burlington, MA + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Needham, MA + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Boston, MA + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Needham, MA + 42 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Quincy, MA + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Boston, MA + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Brighton, MA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Waltham, MA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Rhythm Pharmaceuticals, Inc.
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 4+
- RecruitingHealthy volunteers
PPDTM CorEvitasTM Obesity (OBR) Drug Effectiveness and Safety Registry
CorEvitas
- Location
- Waltham, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Postnatal Exercise to Activate Baby's Brown Fat
Joslin Diabetes Center
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteers
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
Boston Children's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 9–12
- RecruitingHealthy volunteers
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
Brigham and Women's Hospital
- Location
- Belmont, MA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
The Physiology of Human Brown Adipose Tissue
Beth Israel Deaconess Medical Center
- Location
- Boston, MA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Exercise, Brain Activity, and Weight Maintenance
Joslin Diabetes Center
- Location
- Boston, MA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteers
Personalized Responses to Dietary Composition Trial 3
Zoe Global Limited
- Location
- Needham, MA
- Eligibility basics
- Ages 18+
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.