Weight loss · North Carolina
Weight loss and obesity studies in North Carolina
41 studies have at least one recruiting site in North Carolina. Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
41 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
AstraZeneca
- Location
- Statesville, NC + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
Novo Nordisk A/S
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Monroe, NC + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Chapel Hill, NC + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Raleigh, NC + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Cary, NC + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Novo Nordisk A/S
- Location
- Greensboro, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Morehead City, NC + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Statesville, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Charlotte, NC + 12 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Wilmington, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
ERX Pharmaceuticals
- Location
- Monroe, NC + 2 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteers
Pregnancy Exercise Mode Effect on Childhood Obesity
East Carolina University
- Location
- Greenville, NC
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteers
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18–39 · Women only
- RecruitingHealthy volunteers
Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1–2
- RecruitingHealthy volunteers
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 7–18
- RecruitingHealthy volunteersPhase 2
Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes
University of Colorado, Denver
- Location
- Durham, NC
- Eligibility basics
- Ages 18–65
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.