Study type
Weight loss and obesity studies recruiting now
Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
365 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Birmingham, AL + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Novo Nordisk A/S
- Location
- San Diego, CA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
Novo Nordisk A/S
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
Novo Nordisk A/S
- Location
- Birmingham, AL + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Phoenix, AZ + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Novo Nordisk A/S
- Location
- Conyers, GA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Fairhope, AL + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Alexander City, AL + 129 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Escondido, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Clearwater, FL + 12 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese Participants
Terrestrial Bio, Inc.
- Location
- Tempe, AZ
- Eligibility basics
- Ages 18–60
- RecruitingPhase 4
A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity
Gila Therapeutics, Inc.
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide…
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Phoenix, AZ + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Regeneron Pharmaceuticals
- Location
- Chandler, AZ + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
ERX Pharmaceuticals
- Location
- Louisville, KY + 2 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1
A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets
Corxel Pharmaceuticals
- Location
- Las Vegas, NV + 1 other US site
- Eligibility basics
- Ages 18–55 · Women only
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity
MBX Biosciences
- Location
- Doral, FL + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
Novo Nordisk A/S
- Location
- Cypress, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
First in Human Study in Subjects With Obesity, But Otherwise Healthy
NeuroBo Pharmaceuticals Inc.
- Location
- Miami, FL
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus
Sun Pharmaceutical Industries Limited
- Location
- Little Rock, AR + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults
Shanghai World Leader Pharmaceutical Co., Ltd.
- Location
- Secaucus, NJ
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Rhythm Pharmaceuticals, Inc.
- Location
- Birmingham, AL + 7 other US sites
- Eligibility basics
- Ages 4+
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.