Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
EMD Serono Research & Development Institute, Inc.
- Location
- Charlotte, NC + 13 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Appello Pharmaceuticals, Inc.
- Location
- Asheville, NC + 29 other US sites
- Eligibility basics
- Ages 30–80
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma
Pfizer
- Location
- Monroe, NC + 6 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Durham, NC + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 3
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
GlaxoSmithKline
- Location
- Winston-Salem, NC + 36 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
GlaxoSmithKline
- Location
- Shelby, NC + 50 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 40–84
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Charlotte, NC + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Disc Medicine, Inc
- Location
- Durham, NC + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Durham, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
ACADIA Pharmaceuticals Inc.
- Location
- Cary, NC + 23 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 2
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
Yarrow Bioscience, Inc.
- Location
- Cary, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Amgen
- Location
- Morehead City, NC + 30 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Amgen
- Location
- Hickory, NC + 69 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
CAR-T Long Term Follow Up (LTFU) Study
Novartis Pharmaceuticals
- Location
- Durham, NC + 38 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Durham, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
Genentech, Inc.
- Location
- Hickory, NC + 1 other US site
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
AstraZeneca
- Location
- Winston-Salem, NC + 30 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Orchestra BioMed, Inc
- Location
- Asheville, NC + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
AstraZeneca
- Location
- Greensboro, NC + 120 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Durham, NC + 25 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Neuron23 Inc.
- Location
- Chapel Hill, NC + 43 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)
Avalyn Pharma Inc.
- Location
- Statesville, NC + 30 other US sites
- Eligibility basics
- Ages 18+