Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization
AstraZeneca
- Location
- New Bern, NC + 15 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.
- Location
- Asheboro, NC + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Jazz Pharmaceuticals
- Location
- Charlotte, NC + 20 other US sites
- Eligibility basics
- Ages 12–75
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
EyeBiotech Ltd.
- Location
- Greensboro, NC + 66 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
Centessa Pharmaceuticals (UK) Limited
- Location
- Denver, NC + 19 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
Study of EVO756 in Adults With Migraine
Evommune, Inc.
- Location
- Asheville, NC + 32 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingPhase 4
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
Vanda Pharmaceuticals
- Location
- Kinston, NC + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
Supernus Pharmaceuticals, Inc.
- Location
- Asheville, NC + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Tyra Biosciences, Inc
- Location
- Durham, NC + 11 other US sites
- Eligibility basics
- Ages 3–10
- RecruitingPhase 2
A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
Akebia Therapeutics
- Location
- New Bern, NC + 28 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Cary, NC + 33 other US sites
- Eligibility basics
- Ages 18–74
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Charlotte, NC + 66 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
AstraZeneca
- Location
- Durham, NC + 18 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 4
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
Amgen
- Location
- Greensboro, NC + 57 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 2/Phase 3
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Janssen Research & Development, LLC
- Location
- Asheville, NC + 44 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Immunovant Sciences GmbH
- Location
- Charlotte, NC + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease
Merida Biosciences
- Location
- Morehead City, NC + 10 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
Expedition Therapeutics, Inc
- Location
- Shelby, NC + 21 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
GlaxoSmithKline
- Location
- Morehead City, NC + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
Novo Nordisk A/S
- Location
- Greensboro, NC + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
UCB Biopharma SRL
- Location
- Charlotte, NC + 41 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
Atsena Therapeutics Inc.
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Ages 5+
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Intra-Cellular Therapies, Inc.
- Location
- Charlotte, NC + 17 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
Biogen
- Location
- Greenville, NC + 14 other US sites
- Eligibility basics
- Ages 18–80