Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 55–84
- RecruitingPhase 3
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
Regeneron Pharmaceuticals
- Location
- Chapel Hill, NC + 12 other US sites
- Eligibility basics
- Ages 6 mo–6
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
Octapharma
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 2/Phase 3
Nectero EAST System Clinical Study
Nectero Medical, Inc.
- Location
- Durham, NC + 35 other US sites
- Eligibility basics
- Ages 21–85
- RecruitingPhase 3
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
Octapharma
- Location
- Durham, NC + 8 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
BiVACOR® Total Artificial Heart Early Feasibility Study
BiVACOR Inc.
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- Charlotte, NC + 58 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Genentech, Inc.
- Location
- Monroe, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
Pfizer
- Location
- Statesville, NC + 10 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Charlotte, NC + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Charlotte, NC + 82 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Novartis Pharmaceuticals
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
Crystalys Therapeutics
- Location
- Charlotte, NC + 40 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
ViiV Healthcare
- Location
- Greensboro, NC + 36 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
Novo Nordisk A/S
- Location
- Statesville, NC + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
Novo Nordisk A/S
- Location
- Greensboro, NC + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
Mercator MedSystems, Inc.
- Location
- Raleigh, NC + 17 other US sites
- Eligibility basics
- Ages 18–89
- RecruitingPhase 2/Phase 3
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Janssen Research & Development, LLC
- Location
- Charlotte, NC + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Effect of Patiromer in Children Under 12 Years of Age With High Blood Potassium Levels
Vifor Pharma, Inc.
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 0 mo–11
- RecruitingPhase 3
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- Recruiting
Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation
C. R. Bard
- Location
- Huntersville, NC + 32 other US sites
- Eligibility basics
- Ages 22–70 · Women only
- Recruiting
INHANCE Stemless Reverse Shoulder IDE
DePuy Orthopaedics
- Location
- Charlotte, NC + 13 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 11 other US sites
- Eligibility basics
- Ages 18–45 · Women only