Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Takeda
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
- Location
- Chapel Hill, NC + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
CRISPR Therapeutics AG
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia
Takeda
- Location
- Denver, NC + 16 other US sites
- Eligibility basics
- Ages 18–71
- RecruitingPhase 3
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Novo Nordisk A/S
- Location
- Durham, NC + 42 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Morehead City, NC + 46 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Clinical Outcomes of 3D Printed and Milled Complete Dentures
Dentsply Sirona Implants and Consumables
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- Recruiting
Post-market Safety and Effectiveness of the CORUS-LX System in Improving Lumbar Interbody Fusion Outcomes
Providence Medical Technology, Inc.
- Location
- Wilmington, NC + 9 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic Hypoparathyroidism
Calcilytix Therapeutics, Inc., a BridgeBio company
- Location
- Greenville, NC + 3 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 3
Brexanolone Lifting Outcomes Of Moms
Lipocine Inc.
- Location
- Chapel Hill, NC + 15 other US sites
- Eligibility basics
- Ages 15–45 · Women only
- RecruitingPhase 3
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Epygenix
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 3
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Pharmazz, Inc.
- Location
- Greensboro, NC + 13 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Raleigh, NC + 32 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Biosense Webster, Inc.
- Location
- Raleigh, NC + 9 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Edwards Lifesciences
- Location
- Chapel Hill, NC + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
AbbVie
- Location
- Charlotte, NC + 87 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 2
A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
Locus Biosciences
- Location
- Raleigh, NC + 11 other US sites
- Eligibility basics
- Ages 18–75 · Women only
- RecruitingPhase 3
Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)
Biotest
- Location
- Winston-Salem, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
VIVEX Biologics, Inc.
- Location
- New Bern, NC + 18 other US sites
- Eligibility basics
- Ages 22–85
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
Basilea Pharmaceutica
- Location
- Chapel Hill, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Safety, Tolerability, and Efficacy of NVG-2089 in Participants With Immune Thrombocytopenia
Nuvig Therapeutics, Inc.
- Location
- Greenville, NC + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)
Vega Therapeutics, Inc
- Location
- Morrisville, NC + 13 other US sites
- Eligibility basics
- Ages 12–75
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
Harmony Biosciences Management, Inc.
- Location
- Gastonia, NC + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis
Fate Therapeutics
- Location
- Fayetteville, NC + 11 other US sites
- Eligibility basics
- Ages 12–70