Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Adverum Biotechnologies, Inc.
- Location
- Asheville, NC + 78 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
Reunion Neuroscience Inc
- Location
- Chapel Hill, NC + 26 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
AstraZeneca
- Location
- Charlotte, NC + 9 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
Sanofi
- Location
- Durham, NC + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
E-Star BioTech, LLC
- Location
- Monroe, NC + 21 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
Study of GS-0415 and How It Works in People With HIV
Gilead Sciences
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Hydrus® Microstent New Enrollment Post-Approval Study
Alcon Research
- Location
- Southern Pines, NC + 12 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Greensboro, NC + 43 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Effectiveness and Safety of OviTex® PRS in Breast Reconstruction
Tela Bio Inc
- Location
- Raleigh, NC + 2 other US sites
- Eligibility basics
- Ages 22–75 · Women only
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Monroe, NC + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
Novartis Pharmaceuticals
- Location
- Chapel Hill, NC + 39 other US sites
- Eligibility basics
- Ages 21–70
- Recruiting
A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1…
Aqua Medical, Inc.
- Location
- Chapel Hill, NC + 3 other US sites
- Eligibility basics
- Ages 22–65
- RecruitingPhase 3
Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
Vanda Pharmaceuticals
- Location
- Wilmington, NC + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Chapel Hill, NC + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)
GlaxoSmithKline
- Location
- Charlotte, NC + 93 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)
TG Therapeutics, Inc.
- Location
- New Bern, NC + 4 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Axon Therapies, Inc.
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Takeda
- Location
- Asheville, NC + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
Arrowhead Pharmaceuticals
- Location
- Greensboro, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Evaluation of the Efficacy and Safety of THRV-1268 in Participants With Long QT Syndrome Type 2 (LQTS2) and Type 3 (LQTS3)
Thryv Therapeutics, Inc.
- Location
- Wilmington, NC + 6 other US sites
- Eligibility basics
- Ages 15+
- RecruitingPhase 2/Phase 3
A Study of Buntanetap in Participants With PD
Annovis Bio Inc.
- Location
- Durham, NC + 26 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
An Efficacy and Safety Study of DFL24498 in the Treatment of AKC
Dompé Farmaceutici S.p.A
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Ages 10–65
- RecruitingPhase 1/Phase 2
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X, Inc.
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Novo Nordisk A/S
- Location
- Durham, NC + 8 other US sites
- Eligibility basics
- Ages 2+