Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
AstraZeneca
- Location
- Raleigh, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
AbbVie
- Location
- Chapel Hill, NC + 11 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Zydus Therapeutics Inc.
- Location
- Winston-Salem, NC + 13 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.
Kuros Biosurgery AG
- Location
- Charlotte, NC + 6 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Morehead City, NC + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 1/Phase 2
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
CytoAgents, Inc.
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children
Kaneka Medical America LLC
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Up to age 21
- Recruiting
Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
Kaneka Medical America LLC
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Up to age 75
- RecruitingPhase 2/Phase 3
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
Oculis
- Location
- Garner, NC + 11 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
DreaMed Diabetes
- Location
- Morehead City, NC + 4 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant Migraine
Salvia BioElectronics
- Location
- Charlotte, NC + 2 other US sites
- Eligibility basics
- Ages 22–84
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
Harmony Biosciences Management, Inc.
- Location
- Gastonia, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)
Locate Bio Pty Ltd
- Location
- Pinehurst, NC + 2 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 3
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Novartis Pharmaceuticals
- Location
- Raleigh, NC + 42 other US sites
- Eligibility basics
- Ages 40–70
- Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
EmStop Inc
- Location
- Asheville, NC + 6 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
- Location
- Charlotte, NC + 31 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 3
A Study of Pitolisant in Patients With Prader-Willi Syndrome
Harmony Biosciences Management, Inc.
- Location
- Morrisville, NC + 18 other US sites
- Eligibility basics
- Ages 6+
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Asheville, NC + 54 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
Relay Therapeutics, Inc.
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Chapel Hill, NC + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
AbbVie
- Location
- Wilmington, NC + 10 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Eli Lilly and Company
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2/Phase 3
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
Protara Therapeutics
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 12+