Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Wilmington, NC + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 2
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
NMD Pharma A/S
- Location
- Chapel Hill, NC + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Boehringer Ingelheim
- Location
- Charlotte, NC + 9 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty
Synaptrix, Inc.
- Location
- Chapel Hill, NC + 4 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Charlotte, NC + 111 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
Pfizer
- Location
- Durham, NC + 26 other US sites
- Eligibility basics
- Ages 12+
- Recruiting
Evaluating Clinical Hiatal Hernia Outcomes Using OviTex®
Tela Bio Inc
- Location
- Charlotte, NC + 4 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease
Denali Therapeutics Inc.
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Descartes-08 in Autoantibody Myositis
Cartesian Therapeutics
- Location
- Chapel Hill, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Statesville, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Asheville, NC + 42 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Inmagene LLC
- Location
- Charlotte, NC + 15 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
GlaxoSmithKline
- Location
- Winston-Salem, NC + 29 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Dentsply Sirona Implants and Consumables
- Location
- Huntersville, NC + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)
Travere Therapeutics, Inc.
- Location
- Morrisville, NC
- Eligibility basics
- Ages 5–65
- RecruitingPhase 3
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Charlotte, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Charlotte, NC + 12 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Charlotte, NC + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Eli Lilly and Company
- Location
- Chapel Hill, NC + 39 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 3
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
X4 Pharmaceuticals
- Location
- Durham, NC + 20 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
BOOM-IBD2 Pivotal Clinical Trial
Boomerang Medical
- Location
- Chapel Hill, NC + 15 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
AbbVie
- Location
- Winston-Salem, NC + 14 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
EyeBiotech Ltd.
- Location
- Asheville, NC + 51 other US sites
- Eligibility basics
- Ages 50+