Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- Durham, NC + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
BlueRock Therapeutics
- Location
- Durham, NC + 33 other US sites
- Eligibility basics
- Ages 45–75
- Recruiting
ATLAS (AltaValve) Pivotal Trial
4C Medical Technologies, Inc.
- Location
- Charlotte, NC + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease
GlaxoSmithKline
- Location
- Chapel Hill, NC + 28 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
FORWARD CAD IDE Study
Shockwave Medical, Inc.
- Location
- Raleigh, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
Insulet Corporation
- Location
- Asheville, NC + 25 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
Aurinia Pharmaceuticals Inc.
- Location
- Charlotte, NC + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab
PPD Development, LP
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart
PPD Development, LP
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab
PPD Development, LP
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)
PPD Development, LP
- Location
- Chapel Hill, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study of BHV-1300 in Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Greenville, NC + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Artiva Biotherapeutics, Inc.
- Location
- Charlotte, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
W.L.Gore & Associates
- Location
- Charlotte, NC + 30 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Immunovant Sciences GmbH
- Location
- Chapel Hill, NC + 47 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Monroe, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- Monroe, NC + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Axsome Therapeutics, Inc.
- Location
- Raleigh, NC + 35 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
GlaxoSmithKline
- Location
- Winston-Salem, NC + 37 other US sites
- Eligibility basics
- Ages 40–75
- RecruitingPhase 2
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
RAPT Therapeutics, Inc., a member of the GSK plc group of companies
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingPhase 2
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
Kinaset Therapeutics Inc
- Location
- Charlotte, NC + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Janssen Research & Development, LLC
- Location
- Durham, NC + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Maze Therapeutics
- Location
- Durham, NC + 58 other US sites
- Eligibility basics
- Ages 18–68
- RecruitingPhase 2
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Raleigh, NC + 22 other US sites
- Eligibility basics
- Ages 18–64