Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Fayetteville, NC + 62 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Axsome Therapeutics, Inc.
- Location
- Denver, NC + 37 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Edwards Lifesciences
- Location
- Durham, NC + 20 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle
Vericel Corporation
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 17–65
- RecruitingPhase 2
A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
ViiV Healthcare
- Location
- Charlotte, NC + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Chugai Pharmaceutical
- Location
- Chapel Hill, NC + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Asheville, NC + 69 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
Innova Vascular, Inc.
- Location
- Chapel Hill, NC + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 1 mo–18
- RecruitingPhase 2
A Study of TAK-360 in Adults With Idiopathic Hypersomnia
Takeda
- Location
- Denver, NC + 12 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
MISHA Post-Market Clinical Study
Moximed
- Location
- Raleigh, NC + 3 other US sites
- Eligibility basics
- Ages 25–65
- RecruitingPhase 1
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
United Therapeutics
- Location
- Durham, NC + 73 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)
FemPulse Corporation
- Location
- Charlotte, NC + 11 other US sites
- Eligibility basics
- Ages 21+ · Women only
- Recruiting
Clinical Outcomes Study of the Nexel Total Elbow
Zimmer Biomet
- Location
- Charlotte, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
Pfizer
- Location
- Durham, NC + 30 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 2
A Phase 2 Study of CRD-4730 in CPVT
Cardurion Pharmaceuticals, Inc.
- Location
- Morrisville, NC + 4 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Wilmington, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
FiberLocker® System Augmentation of Rotator Cuff Repairs
ZuriMED Technologies Inc.
- Location
- Winston-Salem, NC + 3 other US sites
- Eligibility basics
- Ages 30–70
- RecruitingPhase 2
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
GlaxoSmithKline
- Location
- Fayetteville, NC + 24 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Priovant Therapeutics, Inc.
- Location
- Durham, NC + 44 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
Medtronic Cardiovascular
- Location
- Winston-Salem, NC + 27 other US sites
- Eligibility basics
- Ages 20+
- Recruiting
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
AquaPass Medical Ltd.
- Location
- Asheville, NC + 7 other US sites
- Eligibility basics
- Ages 21–79
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Durham, NC + 46 other US sites
- Eligibility basics
- Ages 50+