Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery
Corza Medical GmbH
- Location
- Charlotte, NC + 8 other US sites
- Eligibility basics
- Ages 1 mo+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Durham, NC + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
Ansun Biopharma, Inc.
- Location
- Durham, NC + 18 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Winston-Salem, NC + 29 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 2
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)
Shionogi
- Location
- Durham, NC + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
ERX Pharmaceuticals
- Location
- Monroe, NC + 2 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 3
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
Takeda
- Location
- Greenville, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Global Trial in APG2575 for Patients With CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Greenville, NC + 10 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Raleigh, NC + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney…
Alexion Pharmaceuticals, Inc.
- Location
- Durham, NC + 28 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Charlotte, NC + 46 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
The THOR IDE Study
Philips Clinical & Medical Affairs Global
- Location
- Cary, NC + 28 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
Rivermark Medical
- Location
- Raleigh, NC + 18 other US sites
- Eligibility basics
- Ages 45+ · Men only
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Chapel Hill, NC + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Neurona Therapeutics
- Location
- Charlotte, NC + 34 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Chapel Hill, NC + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 1
Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients
Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm)
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–65
- Recruiting
KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure
SterileCare Inc.
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 1 mo–18
- RecruitingPhase 3
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Ardelyx
- Location
- Cary, NC + 108 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Use of CereGate Therapy for Freezing of Gait in PD
CereGate Inc.
- Location
- Winston-Salem, NC + 6 other US sites
- Eligibility basics
- Ages 21–80
- RecruitingPhase 1/Phase 2
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
Exegi Pharma, LLC
- Location
- Chapel Hill, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)
Dyne Therapeutics
- Location
- Hillsborough, NC
- Eligibility basics
- Ages 4–18 · Men only
- RecruitingPhase 1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Fate Therapeutics
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 12–70
- RecruitingPhase 2
A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature
BioMarin Pharmaceutical
- Location
- Chapel Hill, NC + 30 other US sites
- Eligibility basics
- Ages 3–11