Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Kodiak Sciences Inc
- Location
- Cary, NC + 47 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
Kodiak Sciences Inc
- Location
- Cary, NC + 47 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- Charlotte, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
Rivus Pharmaceuticals, Inc.
- Location
- Fayetteville, NC + 30 other US sites
- Eligibility basics
- Ages 30+
- Recruiting
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
W.L.Gore & Associates
- Location
- Charlotte, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
AbbVie
- Location
- Charlotte, NC + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Travere Therapeutics, Inc.
- Location
- Chapel Hill, NC + 16 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 1
A Study Assessing KB407 for the Treatment of Cystic Fibrosis
Krystal Biotech, Inc.
- Location
- Winston-Salem, NC + 5 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Multi-center, Early Feasibility Study of Using the Mechanical Tissue Resuscitation™ (MTR®) Therapy System for Removal of Excess Fluid in Subjects Who Have Had a Portion of Their Skull Removed to Expose the Dura/Brain…
Renovo Concepts, Inc.
- Location
- Winston-Salem, NC + 2 other US sites
- Eligibility basics
- Ages 22–65
- Recruiting
J-Valve Transfemoral Pivotal Study
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC
- Location
- Charlotte, NC + 33 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia
argenx
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
Zucara Therapeutics Inc.
- Location
- Morehead City, NC + 36 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
SELUTION4BTK Trial
M.A. Med Alliance S.A.
- Location
- Raleigh, NC + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
Amgen
- Location
- Charlotte, NC + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Alto Neuroscience
- Location
- Charlotte, NC + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
- Location
- Denver, NC + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
- Location
- Denver, NC + 18 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Drug-Drug Interaction Study of ABP-671 in Gout Patients
Atom Therapeutics Co., Ltd
- Location
- Cary, NC
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
ReAlta Life Sciences, Inc.
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 4
A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab
Alexion Pharmaceuticals, Inc.
- Location
- Raleigh, NC
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
Merck Sharp & Dohme LLC
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)
Cerus Endovascular, Inc.
- Location
- Raleigh, NC + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Durham, NC + 36 other US sites
- Eligibility basics
- Ages 18–90