Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Italfarmaco
- Location
- Chapel Hill, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
ModernaTX, Inc.
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 1+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Vertex Pharmaceuticals Incorporated
- Location
- Charlotte, NC + 2 other US sites
- Eligibility basics
- Ages 12–35
- Recruiting
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes
3ive Labs
- Location
- Chapel Hill, NC + 3 other US sites
- Eligibility basics
- Ages 22–85
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Mirador Therapeutics, Inc.
- Location
- High Point, NC + 42 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2/Phase 3
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Takeda
- Location
- Denver, NC + 18 other US sites
- Eligibility basics
- Ages 16–70
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Kinston, NC + 17 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
Direct Biologics, LLC
- Location
- Durham, NC + 30 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
Stratpharma AG
- Location
- Fayetteville, NC + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 2/Phase 3
Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis
argenx
- Location
- Chapel Hill, NC + 2 other US sites
- Eligibility basics
- Ages 2–18
- Recruiting
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Piomic Medical
- Location
- Chapel Hill, NC + 24 other US sites
- Eligibility basics
- Ages 22–90
- Recruiting
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
- Location
- Charlotte, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia
Karyopharm Therapeutics Inc
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
VistaGen Therapeutics, Inc.
- Location
- Cary, NC + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
Dimerix Bioscience Pty Ltd
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 2
Open-label Extension Study in Participants With Early Alzheimer's Disease
GlaxoSmithKline
- Location
- Matthews, NC + 8 other US sites
- Eligibility basics
- Ages 50–85
- Recruiting
Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)
Coologics, Inc
- Location
- Raleigh, NC + 7 other US sites
- Eligibility basics
- Ages 22–49 · Women only
- Recruiting
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
InMode MD Ltd.
- Location
- Winston-Salem, NC + 4 other US sites
- Eligibility basics
- Ages 22–80 · Women only
- RecruitingPhase 3
Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata
Sun Pharmaceutical Industries, Inc.
- Location
- Cary, NC + 53 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 1/Phase 2
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
ModernaTX, Inc.
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
Amicus Therapeutics
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 2
Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
Vaneltix Pharma, Inc.
- Location
- Winston-Salem, NC + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Takeda
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Ages 18+